Endocrinology Question 1

A 24 year-old woman, Maria Aquino, presents with two-month history of weight loss, anxiety, hyperdefecation, scant menses, palpitations and hear intolerance.  On exam, she appears anxious.

Aquino has: HR 126, BP 140/68, a fine tremor, very brisk reflexes, mildly enlarged thyroid (30 g), sTSH <0.01, free T4 46 (N 7.5-16), free T3 12 (N 3.5-6)

What are the two most likely diagnoses in your differential? How do you differentiate them?

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