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How is the presentation different between patients with primary versus secondary cortisol deficiency?
| Primary | Secondary |
| Hyperkalemia, Hyperpigmented, May have other autoimmune diseases or another reason for adrenal failure, High ACTH |
May have evidence of sellar space-occupying lesion, May have other pituitary hormone deficiencies or excesses, ACTH is not elevated |
(Both have hyponatremia)
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