Endocrinology Question 27 Instructor

Lucy Rodriguez is a 24 year-old woman who has come to see you because her periods are very irregular and she is bothered by increasing acne and facial hair on her upper lip and cheeks. Her BMI is 28, and her Ferriman-Gallwey score is 8. You suspect PCOS, but how do you diagnose it?

Rotterdam criteria (at least 2/3 of the following):

  • Hyperandrogenism (physical and/or biochemical)
  • Anovulation
  • Polycystic ovaries on imaging

Plus none of the following:

  • Cushing’s syndrome
  • Acromegaly
  • Congenital adrenal hyperplasia
  • Adrenal or ovarian androgen-producing tumor
    • the latter two are often associated with virilization, (i.e. deepened voice, male musculature, loss of breast tissue, cliteromegaly)

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