A 40 year-old man, Maurice LeBlanc, has his lipids checked for the first time. He has no significant past medical history, but a positive family history of early CAD.
|Total cholesterol||8.8 mmol/L|
What is the lipid abnormality?
Elevated LDL cholesterol.
List three physical (non-vascular) signs that should be looked for.
- Arcus (circus) cornealis
- Tendinous xanthomata
(NOT eruptive xanthoma, nor lipemia retinalis which are seen with high triglycerides)
List 3 potential primary causes and 3 secondary causes for this lipid abnormality.
- Polygenic hypercholesterolemia
- Familial hypercholesterolemia
- Familial combined hyperlipidemia
- Biliary cirrhosis
- Nephrotic syndrome
- Anorexia nervosa