Endocrinology Question 9 Instructor

List 7 classes of drugs besides insulin that lower glucose, and their main mechanism of action.

Drug Class Mechanism of Action
Biguanide (Metformin) Reduces hepatic glucose production,
Increases insulin sensitivity
Sulfonylureas Insulin release via stimulation of the sulfonylurea receptor
DPP-4 inhibitors
(Sitagliptin/saxagliptin)
Inhibit breakdown of GLP-1, GIP
Incretins that stimulate insulin release in response to diet
GLP-1 analog (Liraglutide) See above
Thiazolidinediones
(pioglitazone, rosiglitazone)
PPARg agonist,
Insulin sensitizer

Subscribe to Pearls

Uncle Sam wants you to subscribe to Medical Pearls

Subscribe today! It’s always free, and you can easily unsubscribe at any time. We will never share your email address. Subscribe to...

Multiple Pearls
Cardiology Pearls
Endocrinology Pearls
Hematology Pearls
Nephrology Pearls
Rheumatology Pearls
Transplant Pearls
General Internal Medicine Pearls
Instructor Pearls

Subscribe to receive your pearls today—it's free!