A 55 year-old woman is admitted from home with pneumonia.
- What are the most likely pathogens in this case?
- What empiric antibiotic therapy would you treat her with?
- How would your management change if this woman was HIV+ with evidence of Pneumocystis jirovecii pneumonia (PJP)?
- TMP-SMX (septra) 15-20mg/kg PO/IV q6-8hr daily for 21d
- Dapsone with trimethoprim can be used as an alternative therapy