A 22 year old female is referred to your clinic for a lifelong history of easy bruising and heavy menstrual bleeding starting at menarche.
- Is this bleeding history significant? Are there any clinical prediction rules that may help in defining pre-hemostatic test probability?
- She is found to have von Willebrand disease on hemostatic testing. What is von Willebrand disease?
- What is the initial screen for von Willebrand disease? What are the subsequent tests required to further define the diagnosis?