Nephrology Question 19

One patient has a GFR of 5 ml/min and one patient has a GFR of 120 ml/min. Both have a daily urine output of 1.8 L per day.

  1. Please explain how they both can have the same daily urine output despite such large differences in GFR.
  2. In a patient with a GFR of 5 ml/min, can diuretics increase urine output?
  3. Do diuretics have any impact on clearance of uremic toxins?
  4. Do diuretics have any impact on clearance of potassium?

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