Transplant Question 14 Instructor

Compare cyclosporine, tacrolimus, sirolimus, steroids, azathioprine and mycophenolate for their effect on the risk of hypertension, hyperlipidemia, and hyperglycemia post-transplant.

Hypertension is a common side effect of cyclosporine, tacrolimus and steroids.

Hyperlipidemia is more commonly seen with cyclosporine than tacrolimus. Sirolimus and steroids also cause hyperlipidemia.

Hyperglycemia is more common with tacrolimus than cyclosporine. Steroids can also cause hyperglycemia. Sirolimus has also been reported to increase the risk for diabetes.

Azathioprine and mycophenolate do not affect the cardiovascular risk profile.

A summary of the effects on cardiovascular risk factors can be found here.

Subscribe to Pearls

Uncle Sam wants you to subscribe to Medical Pearls

Subscribe today! It’s always free, and you can easily unsubscribe at any time. We will never share your email address. Subscribe to...

Multiple Pearls
Cardiology Pearls
Endocrinology Pearls
Hematology Pearls
Nephrology Pearls
Rheumatology Pearls
Transplant Pearls
General Internal Medicine Pearls
Instructor Pearls

Subscribe to receive your pearls today—it's free!