Hematology Question 7

The following results were found in a 28-year-old woman as part of a work up for infertility. She has never had a history of bleeding or bruising nor does she have a family history for bleeding.

Test Patient Reference Range
PT 11s 11-14s
APTT 44s 23-35s
Fibrinogen 2.9g/L 1.5-4.0g/L
Thrombin Time 12s 10-13s
  1. What are the causes of an elevated PTT in a non-bleeding patient?
  2. Describe the additional tests that would be required to make a diagnosis in this case.
  3. What is a lupus anti-coagulant and how does it alter the PTT?

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