Transplant Question 19

A patient is 6 months post-renal transplant, on tacrolimus (trough levels between 10 and 12 ng/mL), mycophenolate mofetil 1 g bid, and prednisone 7.5 mg daily. Her creatinine jumps from 120 to 200 µmol/L. A renal biopsy is reported as, “Acute polyomavirus nephropathy.”

How would you treat this patient?